Sarcoidosis is an inflammatory disease that affects one or more organs but most commonly affects the lungs and lymph glands. As a result of the inflammation, abnormal lumps or nodules (called granulomas) form in one or more organs of the body. These granulomas may change the normal structure and possibly the function of the affected organ(s). Many people clear up without any treatment within a few years. However some may have long term or severe disease. Some symptoms may be improved with the use of anti-inflammatory drugs such as ibuprofen. In cases where the condition causes significant health problems steroids such as prednisone are indicated. Alternatively, medications such as methotrexate,chloroquine, or azathioprine may occasionally be used in an effort to decrease the side effects of steroids. The risk of death is between one and seven percent. There is a less than five percent chance of the disease returning in someone who has had it previously.